The European Commission has prioritised the development of mHealth in the Digital Single Market strategy, launching a Green Paper and Public Consultation in 2014. In response to concerns over privacy, security and the reliability of information provided by wellbeing apps, the Commission facilitated the design of an industry-led privacy Code of Conduct and set up a working group on mHealth assessment guidelines, aiming to provide a certified quality of data essential to increasing the integration of mHealth technologies into the primary healthcare systems. Despite these measures, mobile telemedicine remains a grey legal area, with liability for damages arising from the use of mHealth solutions still unclear. Moreover, problems persist in the lack of interoperability between mHealth solutions and EU healthcare systems. This timely symposium will provide a valuable opportunity to assess these challenges and present evidence of mHealth’s potential to transform the way people care for themselves. It will also enable all relevant stakeholders to share and benefit from examples of best practice with experts, practitioners, and policymakers at EU level.